With only six games remaining of the home and away season, each and every round is becoming more important as teams chase an all-important finals spot.
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The exciting round 20 schedule will kick-off with Thursday's key fixture between the Roosters and Eels, which is one of eight matches that will take place in the NRL's Queensland hub across the weekend.
Kiama's Josh Morris, who will make his return to the Roosters line-up this week in place of Billy Smith (ankle), and Albion Park-Oak Flats' Drew Hutchison are just two of numerous South Coast talents that will be on show across the four days.
On the flip side, the Eels will be coached by former Batemans Bay Tiger Brad Arthur.
Then on Friday, the Tigers will take on Warriors, who will be spearheaded by Shellharbour's Euan Aitken in the centres.
Milton-Ulladulla's Jack Murchie who suffered a head knock against South Sydney has not been named.
Later that evening, Moruya's Rhys Kennedy and his Broncos will host the Cowboys at Suncorp Stadium.
Then on Saturday at Rockhampton, the Dragons lock horns with the Rabbitohs.
The Red V's side features Gerringong duo Tariq Sims and Jackson Ford and Park's Adam Clune, while Nowra-born Cody Walker will start at five-eighth for Souths.
Later at Suncorp Stadium, Batemans Bay's Adam O'Brien and his Knights face the Raiders, before the Storm and Panthers battle at the same venue.
Melbourne's side contains Bega's Dale Finucane and former Shellharbour Shark Chris Lewis.
Sunday's slate will kick-off with the Bulldogs and Titans fixture, with the former's side being buoyed by the return of Tathra's Adam Elliott from a cheekbone injury.
The eighth and final match of the weekend will pit the Sharks against the Sea Eagles.
Pambula-born Jack Williams will start from the Sharks' bench, with Narooma's Teig Wilton out with a hamstring injury.
Gerringong's Reuben Garrick will once against start on the wing for the high-flying Sea Eagles.