Premier League champions Liverpool suffered their heaviest ever defeat under manager Juergen Klopp as they were stunned 7-2 at Aston Villa.
Ollie Watkins scored a hat-trick while Jack Grealish grabbed two as Klopp's side lost their 100 per cent start to the season.
Villa, by contrast, have won their first three games and are now second, level on points with fifth-placed Liverpool, three points behind leaders Everton.
"It's hard to lose the way we lost tonight," Liverpool defender Virgil van Dijk said.
"It was one of those performances where we weren't 100 per cent at it from start to finish. Overall we're all disappointed, we shouldn't have lost with the numbers that we did but it's about sticking together and making sure it doesn't happen again."
Earlier on Sunday, Leicester City also lost their 100 per cent start to the season as they were beaten 3-0 at home by West Ham.
Michail Antonio, Pablo Fornals and Jarrod Bowen scored the goals as the Hammers climbed to 10th, while Son Heung Min and Harry Kane scored two goals each as they produced another stunning result, thrashing 10-man Manchester United 6-1.
Watkins slotted past Adrian after just four minutes and things just got worse for Liverpool at Villa Park.
Watkins, who had never scored in the Premier League before, added his second on 22 minutes before Mohamed Salah pulled one back 12 minutes before halftime.
John McGinn restored Villa's two-goal lead and Watkins completed his hat-trick with a header before the break.
Ross Barkley scored on his Villa debut and although Salah pulled another goal back, Grealish added two more to make it Klopp's heaviest defeat as a manager.
"It was a tremendous performance and one that you don't get too often," Villa manager Dean Smith said.
"To do this to the champions, when you've got Juergen Klopp saying to you at the end, 'wow', you know you've done something right."
At Old Trafford, Bruno Fernandes put United ahead from the spot after two minutes but Son and Tanguay Ndombele had Spurs ahead within seven minutes.
United forward Anthony Martial was sent off for striking Erik Lamela in the 28th minute.
Kane and Son continued the scoring spree, Serge Aurier added a fifth and Kane struck his second from the penalty spot to complete the win.
"Manchester United doesn't lose many matches, to lose by six is of course not every day," said Tottenham manager Jose Mourinho after beating his former employers.
"We were the best team. They couldn't stop us ... the performance was very, very impressive."
Second-half goals from Bukayo Saka and Nicolas Pepe helped Arsenal beat Sheffield United 2-1 to go fourth, leaving their opponents second-bottom.
Fulham remain last, also with no points, after they lost 1-0 at home to Wolves, while Moussa Djenepo and Oriel Romeu goals secured Southampton's victory against winless West Brom.
Australian Associated Press